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150399-23-8 Pemetrexed disodium

150399-23-8 Pemetrexed disodium
Product Detailed
Pemetrexed Disodium CAS 150399-23-8 Molecular Formula: C20H19N5Na2O6 Molecular Weight: 471.37

Pemetrexed disodium

USP31

[ Chemical name ] 

N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid,disodium

[ Appearance ] 

white solid

[ Structural formula ]

[  C A S  ]

150399-23-8

[ Executive standard ]

USP31, CP2005

CAS Registry Number: 357166-30-4Character: white or white crystalline powder; odorless,tasteless, easily absorb water;

Solubility: freely soluble In Water,practically insoluble In chloroform, slightly soluable in Methanol;

 Specific Rotation:+10°~16°;

Identification: (1)flame reaction with sodium salt;(2)The reaction time in the chromatogram of the assay preparation coorresponds to that in the chromatogram of the standard preparation, as obtained in the assay;(3)IR: should conform to the standard;PH: 6.5-8.0;Clear and color of solution:should conform to standard;

Related substances:Individual impurity: <0.5%;tatal impurity: <1.0%; Ethanol, Methylene Chloride, ethyl acetate, N,N-dimethylformamide dimethyl acetal: Ethanol < 0.5%, Methylene Chloride<0.06%, ethyl acetate< 0.5%,N,N-dimethylformamide dimethyl acetal< 0.088%;

Assay:not less than 98.5%(on andydrous basid)..

150399-23-8 Pemetrexed disodium



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